Visible-Light Photocatalytic Barbier-Type Reaction of Aziridines and Azetidines with Nonactivated Aldehydes.

Keywords: photocatalysis; Barbier reaction; aziridines; azetidines; C-N bond cleavage EN photocatalysis Barbier reaction aziridines azetidines C-N bond cleavage 1385 1390 6 07/11/23 20230725 NES 230725 Graph C-C bond-formation processes are an essential class of reactions for the construction of the skeletons of organic compounds. Photocatalysis, Barbier reaction, aziridines, azetidines, C-N bond cleavage After the reduction, the radical-anion intermediate B I b smoothly undergoes C-N bond cleavage to deliver the benzyl radical intermediate B II b . [72] Here, we report a visible-light photocatalytic Barbier-type reaction of aziridines and azetidines with nonactivated aldehydes through reductive cleavage of C-N bonds [75] (Scheme 1 C). [Extracted from the article]