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What drives CAR‐T emergent cytopenia?
- Source :
- British Journal of Haematology; Jul2023, Vol. 202 Issue 2, p213-214, 2p
- Publication Year :
- 2023
-
Abstract
- Summary: Prolonged cytopenia after CAR‐T cell therapy is an acknowledged problem. At present, the causes and implications of prolonged cytopenia are unclear. The paper by Kitamura et al identified that prolonged cytopenia is associated with alterations in the bone marrow niche identified before CAR‐T therapy, indicating a potential predictor of this serious side‐effect of treatment. Commentary on: Kitamura et al. Bone marrow microenvironment disruption and sustained inflammation with prolonged haematologic toxicity after CAR T‐cell therapy? Br J Haematol 2023;202:294‐307. [ABSTRACT FROM AUTHOR]
- Subjects :
- BONE marrow
CELLULAR therapy
T cells
Subjects
Details
- Language :
- English
- ISSN :
- 00071048
- Volume :
- 202
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- British Journal of Haematology
- Publication Type :
- Academic Journal
- Accession number :
- 164877161
- Full Text :
- https://doi.org/10.1111/bjh.18790