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Mitral Annular Calcification and Thromboembolic Risk.
- Source :
- Life (2075-1729); Jul2023, Vol. 13 Issue 7, p1568, 13p
- Publication Year :
- 2023
-
Abstract
- Thromboembolic (TE) risk scores used for atrial fibrillation (AF) patients do not include mitral annular calcification (MAC) as a potential indicator of vascular disease. This research evaluated the correlation between MAC and TE risk scores (CHADS<subscript>2</subscript> and CHA<subscript>2</subscript>DS<subscript>2</subscript>-VASc). We compared TE risk score values and clinical and echocardiographic data in patients with and without MAC. We included, prospectively, 103 patients: 40.8% with AF, 83.5% with hypertension, 30.1% with type II diabetes mellitus, 79.6% with chronic heart failure, and 7.8% with a history of stroke. We identified MAC in 50.5% of patients. The mean CHADS<subscript>2</subscript> and CHA<subscript>2</subscript>DS<subscript>2</subscript>-VASc scores were 2.56 ± 1.135 and 4.57 ± 1.61, respectively. In MAC patients, both scores tended to increase significantly compared with the control (2.88 ± 1.114 versus 2.24 ± 1.06, p = 0.005, and 5.21 ± 1.51 versus 3.92 ± 1.46, p < 0.001, respectively). The left ventricular ejection fraction negatively correlated with the presence of MAC (r = −0.254, p = 0.01). The presence of MAC was a risk factor for vascular disease (OR = 2.47, χ<superscript>2</superscript> = 34.32, p < 0001). Conclusions: The presence of MAC is associated with greater TE risk scores and a higher risk of vascular disease. It appears that adding MAC as a vascular disease parameter to TE risk scores may have benefits for patients by improving their predictive value. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 20751729
- Volume :
- 13
- Issue :
- 7
- Database :
- Complementary Index
- Journal :
- Life (2075-1729)
- Publication Type :
- Academic Journal
- Accession number :
- 169325777
- Full Text :
- https://doi.org/10.3390/life13071568