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Lethal varicella-zoster virus reactivation without skin lesions following renal transplantation.

Lethal varicella-zoster virus reactivation without skin lesions following renal transplantation.

Authors :
Jantsch, Jonathan
Schmidt, Barbara
Bardutzky, Jürgen
Bogdan, Christian
Eckardt, Kai-Uwe
Raff, Ulrike
Source :
Nephrology Dialysis Transplantation; Nov2011, Vol. 26 Issue 11, p365-368, 4p
Publication Year :
2011

Abstract

Patients after solid organ transplantation are at increased risk of developing herpes zoster and are more likely to develop major complications such as cutaneous dissemination, post-herpetic neuralgia and visceral organ involvement. We report on a 68-year-old woman being varicella-zoster virus (VZV)-seropositive prior to transplantation, who developed fatal VZV meningoencephalitis after renal transplantation presenting with non-specific neurologic symptoms. The case illustrates that VZV reactivation may occur in renal transplant recipients in the absence of skin lesions. Approaches towards risk assessment pretransplantation and prophylactic regimens for the prevention of VZV recurrence are needed. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09310509
Volume :
26
Issue :
11
Database :
Complementary Index
Journal :
Nephrology Dialysis Transplantation
Publication Type :
Academic Journal
Accession number :
169731623
Full Text :
https://doi.org/10.1093/ndt/gfq542