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Acetic acid-mediated rapid cubic-to-hexagonal (α–β) phase transformation for ultra-bright lanthanide-doped β-NaYF4 nano-bioprobes.
- Source :
- Nano Research; Jul2023, Vol. 16 Issue 7, p10026-10033, 8p
- Publication Year :
- 2023
-
Abstract
- Hexagonal-phase NaYF<subscript>4</subscript> (β-NaYF<subscript>4</subscript>) has been acknowledged to be one of the most efficient doping hosts to prepare bright lanthanide-doped luminescent nano-bioprobes for various biomedical applications. However, to date, it remains a great challenge to synthesize ultra-bright lanthanide-doped β-NaYF<subscript>4</subscript> nano-bioprobes under a low reaction temperature by using conventional synthetic methods. Herein, we first develop an acetic acid (HAc)-mediated coprecipitation method for the preparation of ultra-bright lanthanide-doped β-NaYF<subscript>4</subscript> nanoprobes under a low reaction temperature at 200 °C. Based on a series of comparative spectroscopic investigations, we show that the use of HAc in the reaction environment can not only promote the rapid α–β phase transformation of NaYF<subscript>4</subscript> host at 200 °C within 1 h but also boost the absolute photoluminescence quantum yield (PLQY) of NaYF<subscript>4</subscript> nanocrystals to 30.68% for near-infrared emission and to 3.79% for upconversion luminescence, both of which are amongst the highest values for diverse lanthanide-doped luminescent nanocrystals ever reported. By virtue of their superior near-infrared luminescence, we achieve optical-guided dynamic vasculature imaging in vivo of the whole body at a high spatial resolution (23.8 µm) under 980 nm excitation, indicating its potential for the diagnosis and treatment evaluation of vasculature-related diseases. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 19980124
- Volume :
- 16
- Issue :
- 7
- Database :
- Complementary Index
- Journal :
- Nano Research
- Publication Type :
- Academic Journal
- Accession number :
- 169750788
- Full Text :
- https://doi.org/10.1007/s12274-023-5671-5