Symmetry Analyses of Epidemiological Model for Monkeypox Virus with Atangana–Baleanu Fractional Derivative.

The monkeypox virus causes a respiratory illness called monkeypox, which belongs to the Poxviridae virus family and the Orthopoxvirus genus. Although initially endemic in Africa, it has recently become a global threat with cases worldwide. Using the Antangana–Baleanu fractional order approach, this study aims to propose a new monkeypox transmission model that represents the interaction between the infected human and rodent populations. An iterative method and the fixed-point theorem are used to prove the existence and uniqueness of the symmetry model's system of solutions. It shows that the symmetry model has equilibrium points when there are epidemics and no diseases. As well as the local asymptotic stability of the disease-free equilibrium point, conditions for the endemic equilibrium point's existence have also been demonstrated. For this purpose, the existence of optimal control is first ensured. The aim of the proposed optimal control problem is to minimize both the treatment and prevention costs, and the number of infected individuals. Optimal conditions are acquired Pontryagin's maximum principle is used. Then, the stability of the symmetry model is discussed at monkeypox-free and endemic equilibrium points with treatment strategies to control the spread of the disease. Numerical simulations clearly show how necessary and successful the proposed combined control strategy is in preventing the disease from becoming epidemic. [ABSTRACT FROM AUTHOR]