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Partially hydrolyzed guar gum suppresses the progression of pulmonary arterial hypertension in a SU5416/hypoxia rat model.

Authors :
Sanada, Takayuki J.
Koji Hosomi
Jonguk Park
Akira Naito
Seiichiro Sakao
Nobuhiro Tanabe
Jun Kunisawa
Koichiro Tatsumi
Takuji Suzuki
Source :
Pulmonary Circulation; Jul2023, Vol. 13 Issue 3, p1-6, 6p
Publication Year :
2023

Abstract

This study investigated the effects of partially hydrolyzed guar gum (PHGG) on the development of pulmonary arterial hypertension using a SU5416/hypoxia rat model. Our results demonstrated that PHGG treatment suppressed the development of pulmonary hypertension and vascular remodeling with an altered gut microbiota composition. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20458932
Volume :
13
Issue :
3
Database :
Complementary Index
Journal :
Pulmonary Circulation
Publication Type :
Academic Journal
Accession number :
171302723
Full Text :
https://doi.org/10.1002/pul2.12266