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Cytohistological Correlation of Langerhans Cell Histiocytosis of the Spine in a Young Adult.
- Source :
- Archives of Medicine & Health Sciences; Jan-Jun2023, Vol. 11 Issue 1, p137-140, 4p
- Publication Year :
- 2023
-
Abstract
- Langerhans cell histiocytosis (LCH) is a rare multisystem disorder with a common histopathological finding of Langerhans-type cell proliferation mixed with a milieu of inflammatory cells. Bone involvement is a common presentation occurring in children and young adults. Recent studies using cell-specific gene expression profiling suggest that LCH arises from bone marrow-derived immature myeloid dendritic cells. We present a case of solitary LCH of cervical vertebrae in a young adult with pain and numbness in the shoulder diagnosed on fine-needle aspiration and confirmed on histopathology and immunohistochemistry. It was treated with tumor resection and stabilization of the vertebrae. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 23214848
- Volume :
- 11
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Archives of Medicine & Health Sciences
- Publication Type :
- Academic Journal
- Accession number :
- 171790583
- Full Text :
- https://doi.org/10.4103/amhs.amhs_18_23