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Cytohistological Correlation of Langerhans Cell Histiocytosis of the Spine in a Young Adult.

Authors :
Asotra, Sarita
Sharma, Sudarshan Kumar
Thakur, Suresh
Source :
Archives of Medicine & Health Sciences; Jan-Jun2023, Vol. 11 Issue 1, p137-140, 4p
Publication Year :
2023

Abstract

Langerhans cell histiocytosis (LCH) is a rare multisystem disorder with a common histopathological finding of Langerhans-type cell proliferation mixed with a milieu of inflammatory cells. Bone involvement is a common presentation occurring in children and young adults. Recent studies using cell-specific gene expression profiling suggest that LCH arises from bone marrow-derived immature myeloid dendritic cells. We present a case of solitary LCH of cervical vertebrae in a young adult with pain and numbness in the shoulder diagnosed on fine-needle aspiration and confirmed on histopathology and immunohistochemistry. It was treated with tumor resection and stabilization of the vertebrae. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
23214848
Volume :
11
Issue :
1
Database :
Complementary Index
Journal :
Archives of Medicine & Health Sciences
Publication Type :
Academic Journal
Accession number :
171790583
Full Text :
https://doi.org/10.4103/amhs.amhs_18_23