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Prostaglandin I2 Therapy Promotes Regulatory T Cell Generation in Patients with Pulmonary Arterial Hypertension.
- Source :
- American Journal of Respiratory & Critical Care Medicine; 9/15/2023, Vol. 208 Issue 6, p737-739, 3p
- Publication Year :
- 2023
-
Abstract
- The article focuses on the potential therapeutic effects of prostaglandin I2 (PGI2) in patients with pulmonary arterial hypertension (PAH). Topics include the role of inflammation and immune responses in PAH, the vasoprotective effects of PGI2, and the hypothesis that PGI2 therapy can increase regulatory T cell (Treg) percentages and decrease the T effector cell (Teff) to Treg ratio in PAH patients.
Details
- Language :
- English
- ISSN :
- 1073449X
- Volume :
- 208
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- American Journal of Respiratory & Critical Care Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 172007000
- Full Text :
- https://doi.org/10.1164/rccm.202304-0716LE