Back to Search Start Over

Frequency, species and molecular characterization of oralCandidain hosts of different age in China.

Authors :
Qi, Q. G.
Hu, T.
Zhou, X. D.
Source :
Journal of Oral Pathology & Medicine; Jul2005, Vol. 34 Issue 6, p352-356, 5p
Publication Year :
2005

Abstract

Research indicates that host age is a determining factor in yeast carriage. From the neonatal period, humans go through several dentition periods, and the emergence and substitution of teeth and changes in living habits greatly change the environment of the oral cavity, and therefore influence colonization by oral commensal organisms, certainly includingCandidaspp. No previous study ofCandidacarriage by different age groups divided by dentition has been reported. This study supplies data on the geographical specificity ofC. albicansgenotypic subgroup distribution.All test individuals came from a single geographical locale over a short period. Following mucosal swab sampling, CHROMagarCandida-yeast differential media were used to determine the frequency of carriage and species. AllC. albicansstrains were confirmed by PCR and PCR using primers reported to span a transposable intron region in the 25S rRNA gene was used to determine genotypic subgroups.The results demonstrate that for the tested population, the frequency ofCandidaspecies and the distribution ofC. albicansgenotypic subgroups varied with age group. With increasing age, the frequency ofC. albicansdecreases, non-C. albicansyeasts increases; Genotypic subgroup A is the dominating strain in the oral cavities of healthy young individuals.The influence of dentition substitution on oral yeast carriage was minor.J Oral Pathol Med(2005)34: 352–6 [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09042512
Volume :
34
Issue :
6
Database :
Complementary Index
Journal :
Journal of Oral Pathology & Medicine
Publication Type :
Academic Journal
Accession number :
17205079
Full Text :
https://doi.org/10.1111/j.1600-0714.2005.00326.x