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Zinc oxide surface-functionalized PCL/graphene oxide scaffold: enhanced mechanical and antibacterial properties.
- Source :
- International Journal of Polymeric Materials & Polymeric Biomaterials; 2023, Vol. 72 Issue 18, p1423-1433, 11p
- Publication Year :
- 2023
-
Abstract
- Porous poly caprolactone (PCL)/graphene oxide (GO) scaffold was fabricated using both particulate and foaming agents to yield better control over pore size. Then, the surface of the PCL/GO scaffold was modified by the aminolysis method for further treatment. Needle-like zinc oxide (ZnO) was synthesized and its antibacterial activity was verified by the disk diffusion method. Next, ZnO immobilized onto the aminolyzed PCL/GO scaffold. The mechanical test demonstrated a pronounced increment of young's modulus for the PCL scaffold. It is expected that such an engineered scaffold has a high potential to be used in tissue engineering with minimal irritation due to infections during implantation. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00914037
- Volume :
- 72
- Issue :
- 18
- Database :
- Complementary Index
- Journal :
- International Journal of Polymeric Materials & Polymeric Biomaterials
- Publication Type :
- Academic Journal
- Accession number :
- 172309597
- Full Text :
- https://doi.org/10.1080/00914037.2022.2100373