Back to Search Start Over

Reshaping Our Knowledge: Advancements in Understanding the Immune Response to Human Respiratory Syncytial Virus.

Authors :
Attaianese, Federica
Guiducci, Sara
Trapani, Sandra
Barbati, Federica
Lodi, Lorenzo
Indolfi, Giuseppe
Azzari, Chiara
Ricci, Silvia
Source :
Pathogens; Sep2023, Vol. 12 Issue 9, p1118, 20p
Publication Year :
2023

Abstract

Human respiratory syncytial virus (hRSV) is a significant cause of respiratory tract infections, particularly in young children and older adults. In this review, we aimed to comprehensively summarize what is known about the immune response to hRSV infection. We described the innate and adaptive immune components involved, including the recognition of RSV, the inflammatory response, the role of natural killer (NK) cells, antigen presentation, T cell response, and antibody production. Understanding the complex immune response to hRSV infection is crucial for developing effective interventions against this significant respiratory pathogen. Further investigations into the immune memory generated by hRSV infection and the development of strategies to enhance immune responses may hold promise for the prevention and management of hRSV-associated diseases. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20760817
Volume :
12
Issue :
9
Database :
Complementary Index
Journal :
Pathogens
Publication Type :
Academic Journal
Accession number :
172413323
Full Text :
https://doi.org/10.3390/pathogens12091118