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Photo-induced scandium-catalyzed biomimetic skeleton conversion of lathyrane to naturally rare eupholathone Euphorbia diterpenes.
- Source :
- Chemical Communications; 10/21/2023, Vol. 59 Issue 82, p12290-12293, 4p
- Publication Year :
- 2023
-
Abstract
- The naturally scarce eupholathone-type euphornin E (1) was efficiently prepared from abundant lathyrane-type Euphorbia factor L<subscript>1</subscript>via a visible-light-induced Sc(OTf)<subscript>3</subscript>-catalyzed tandem process. Eupholathones 2 and 3 were also smoothly obtained by changing the reaction solvent. This route provides a convenient method for easily constructing scarce eupholathone- from lathyrane-type Euphorbia diterpenes, and confirms the biogenetic relationship between them from a chemical standpoint. Notably, compound 1 exhibited good anti-HIV activity. [ABSTRACT FROM AUTHOR]
- Subjects :
- DITERPENES
EUPHORBIA
SOLVENTS
Subjects
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 59
- Issue :
- 82
- Database :
- Complementary Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 172918143
- Full Text :
- https://doi.org/10.1039/d3cc03541g