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Exploring potential anti-inflammatory effects of medicinal cannabis.
- Source :
- Supportive Care in Cancer; Dec2023, Vol. 31 Issue 12, p1-8, 8p
- Publication Year :
- 2023
-
Abstract
- Purpose: Inflammation is thought to play a key role in malignant disease and may play a significant part in the expression of cancer-related symptoms. Cannabidiol (CBD) is a bioactive compound in cannabis and is reported to have significant anti-inflammatory properties. Method: Serial C-reactive protein (CRP) levels were measured in all participants recruited to a randomised controlled trial of CBD versus placebo in patients with symptoms related to advanced cancer. A panel of inflammatory cytokines was measured over time in a subset of these patients. Results: There was no difference between the two arms in the trajectory of CRP or cytokine levels from baseline to day 28. Conclusion: We were unable to demonstrate an anti-inflammatory effect of CBD in cancer patients. Trial registration: ANZCTR 26180001220257, registered 20/07/2018. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09414355
- Volume :
- 31
- Issue :
- 12
- Database :
- Complementary Index
- Journal :
- Supportive Care in Cancer
- Publication Type :
- Academic Journal
- Accession number :
- 172999860
- Full Text :
- https://doi.org/10.1007/s00520-023-08069-8