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Transnasal negative pressure therapy for accelerating healing and improving the prognosis of pharyngocutaneous fistula.

Authors :
Hu, Zhangwei
Guo, Xueqin
Chen, Lin
Lei, Wenbin
Source :
Head & Neck; Nov2023, Vol. 45 Issue 11, p2809-2818, 10p
Publication Year :
2023

Abstract

Background: Pharyngocutaneous fistula (PCF) is one of the most common complications of total laryngectomy. This study is to investigate the efficacy of a novel platform called transnasal negative pressure therapy (TNPT) in the management of PCF. Methods: We retrospectively reviewed 47 patients who underwent total laryngectomy between April 2015 and February 2021 and developed PCF in our hospital. We focused on the healing rate, dressing change frequency, and healing time between the TNPT and non‐TNPT groups. The 2 years overall survival (OS) was compared through the log‐rank test. Results: There were 18 patients in the TNPT group and 29 in the non‐TNPT group. There was no significant between‐group difference in the healing rate (chi‐square test). However, the frequency of dressing changes was significantly lower (p < 0.001) and the healing time was significantly shorter (p = 0.0194) in the TNPT group than in the non‐TNPT group. The 2‐year OS rate was significantly higher in the TNPT group (p = 0.0473, log‐rank test). Conclusion: TNPT promoted wound healing after surgery for PCF and improved the 2‐year OS rate. This tool is worthy of clinical application and promotion. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10433074
Volume :
45
Issue :
11
Database :
Complementary Index
Journal :
Head & Neck
Publication Type :
Academic Journal
Accession number :
173054040
Full Text :
https://doi.org/10.1002/hed.27505