Repeatability and reproducibility of hydrogel 3D bioprinting.

The study presents the basic terms of three-dimensional bioprinting and physical, chemical, and biological properties affecting the printability of hydrogel biomaterials. It deals with the principle of evaluating the quality of threedimensional bioprinting. The goal was to design a procedural algorithm to analyze prints produced by extrusion 3D bioprinting critically. Forty-one cylindrical scaffolds were created experimentally from the same material and under varying printing parameters. The settings of the most plausible sample compared to the CAD design were used to 3D bioprint ten cylindrical samples. Analysis of measurement system (ASM) with three operators was used for evaluation. The results showed that the printability measurement system is conditionally suitable. At the same time, the methodology for evaluating the shape similarity of samples through macroscopic pore classification requires re-evaluation and further experiments. [ABSTRACT FROM AUTHOR]