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Structure-Activity and Antioxidant Properties of Quercetin and Its Co2+ Chelate.
- Source :
- International Journal of Secondary Metabolite; Dec2021, Vol. 8 Issue 4, p414-424, 11p
- Publication Year :
- 2021
-
Abstract
- Quercetin and its metal complexes have anti-oxidation, antibacterial, anti-tumor, and kinds of enzymatic activities. Studies in recent years, these activities are very important for health and pharmaceutics. The purpose of this manuscript is to determine the structure-activity relations and antioxidant properties of the Quercetin and Quercetin-Co<superscript>2+</superscript> chelate from a theoretical view and to be used these compounds in the treatment of the diseases. We found that Quercetin is more stable than Quercetin-Co<superscript>2+</superscript> chelate but Quercetin-Co<superscript>2+</superscript> chelate is more conductive and the O22-H bond of the Quercetin molecule has the highest antioxidant activity. The remarkable electron delocalization occurred between the donor (C17-C19) anti bond and acceptor (C13-C15) anti bond with 319.62 kcal/mol stabilization energy in Quercetin. [ABSTRACT FROM AUTHOR]
- Subjects :
- QUERCETIN
ANTIOXIDANT analysis
CHELATES
METAL complexes
ANTIBACTERIAL agents
Subjects
Details
- Language :
- English
- ISSN :
- 21486905
- Volume :
- 8
- Issue :
- 4
- Database :
- Complementary Index
- Journal :
- International Journal of Secondary Metabolite
- Publication Type :
- Academic Journal
- Accession number :
- 173136424
- Full Text :
- https://doi.org/10.21448/ijsm.954992