Correlation of HbA1c and Lipids with Obesity in Patients with Type 2 Diabetes in Pakistani Population.

Objective: To quantify the correlation between Glycated Haemoglobin, Serum Lipids and overweight/obese Type II patients with diabetes. Study Design: Cross-sectional study. Place and Duration of Study: Department of Internal Medicine and Endocrinology/Diabetology, PIMS (FMTI), Islamabad Pakistan, from Jul 2020 to Dec 2020. Methodology: The study population comprised of severely overweight and obese patients of diabetes. Their laboratory investigations for lipid profile and HbA1c levels were measured. Correlation coefficients between lipid profile, HbA1c levels and obesity were computed. Results: In this study, 112 patients of diabetes were included in the study. The mean age of patients was 48.2±3.4 years, and females were slightly greater (29,51.8%). The average BMI level was 31.98±3.32kg/m2. HbA1c was found to be positively correlated with total cholesterol (r= 0.702, p-value, <0.001) and BMI (r= 0.231, p-value, 0.054) and negatively correlated with HDL levels (r=-0.372, p-value, 0.005) in the study patients. HDL was also negatively correlated with BMI levels (r=-0.314, p-value 0.01). Conclusion: HbA1c was positively correlated with BMI and total cholesterol in patients with diabetes. Moreover, HDL significantly negatively correlated with obesity and HbA1c [ABSTRACT FROM AUTHOR]