Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis.

Subjects

Subjects :

CROHN'S disease
GENETIC variation
PHAGOCYTOSIS
GENETIC code
MEDICAL sciences
PULMONARY alveolar proteinosis
CHOLANGITIS

Details

Language :

English

ISSN :

00175749

Volume :

72

Issue :

11

Database :

Complementary Index

Journal :

Gut

Publication Type :

Academic Journal

Accession number :

173836338

Full Text :

https://doi.org/10.1136/gutjnl-2023-329689