Isolation and structure elucidation of antioxidant compounds from stem and root barks of Daphne giraldii.

Two new compounds, aphegiractin A₁/A₂ (1a/1b), and seven known compounds were isolated by phytochemical work on EtOAc-soluble ingredients extracted from stem and root barks of Daphne giraldii. Their structures were established based on extensive spectroscopic methods, including HRESIMS, CD experiments, 1D and 2D NMR. All compounds were evaluated for their antioxidant activity to DPPH, ABTS radical scavenging activity and inhibitory activity on tyrosinase. Of these compounds, compound 3 exhibited significant antioxidant activities. [ABSTRACT FROM AUTHOR]