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hipFG: high-throughput harmonization and integration pipeline for functional genomics data.

Authors :
Cifello, Jeffrey
Kuksa, Pavel P
Saravanan, Naveensri
Valladares, Otto
Wang, Li-San
Leung, Yuk Yee
Source :
Bioinformatics; Nov2023, Vol. 39 Issue 11, p1-5, 5p
Publication Year :
2023

Abstract

Summary Preparing functional genomic (FG) data with diverse assay types and file formats for integration into analysis workflows that interpret genome-wide association and other studies is a significant and time-consuming challenge. Here we introduce hipFG (Harmonization and Integration Pipeline for Functional Genomics), an automatically customized pipeline for efficient and scalable normalization of heterogenous FG data collections into standardized, indexed, rapidly searchable analysis-ready datasets while accounting for FG datatypes (e.g. chromatin interactions, genomic intervals, quantitative trait loci). Availability and implementation hipFG is freely available at https://bitbucket.org/wanglab-upenn/hipFG. A Docker container is available at https://hub.docker.com/r/wanglab/hipfg. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13674803
Volume :
39
Issue :
11
Database :
Complementary Index
Journal :
Bioinformatics
Publication Type :
Academic Journal
Accession number :
174011567
Full Text :
https://doi.org/10.1093/bioinformatics/btad673