Researcher at Mie University Graduate School of Medicine Zeroes in on Age-Related Macular Degeneration (Subclinical Ocular Changes after Intravitreal Injections of Different Anti-VEGF Agents for Neovascular Age-Related Macular Degeneration).

A recent report discusses research on age-related macular degeneration (AMD) conducted at Mie University Graduate School of Medicine in Japan. The study focused on the effects of different anti-VEGF agents, including aflibercept, brolucizumab, and faricimab, on patients with neovascular AMD. The researchers found that while none of the patients experienced intraocular inflammations after the injections, the aqueous flare value (AFV) increased significantly in the aflibercept and faricimab groups. Additionally, the implicit time was prolonged in the brolucizumab group, indicating potential transient retinal disturbances. These findings suggest that brolucizumab may have unique effects on the retina that are not easily detectable through standard ophthalmologic examinations. [Extracted from the article]