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Post-malaria neurological syndrome (PMNS): a rare case report with brain biopsy findings.

Authors :
Alawad, Mouhammad J
Almayoof, Moustafa
Al bozom, Adel
Alkhidir, Taha
Emam, Saeed S
Farfar, Khalifa
Source :
BMC Infectious Diseases; 12/19/2023, Vol. 23 Issue 1, p1-7, 7p
Publication Year :
2023

Abstract

Post-malaria neurological syndrome (PMNS) is a rare, self-limiting condition that presents with a wide range of neurological manifestations after clearance of malarial infection, especially 혗혭혢혴혮혰혥혪혶혮 f혢혭혤혪혱혢혳혶혮, most patients recover without residual deficits. Here we present a case of a 29-year-old, male with a recent history of malaria treated successfully, who presented due to a generalized tonic-clonic seizure, without any other neurological symptoms, the examination and labs were unremarkable, he underwent a computer tomography (CT) scan and Magnetic resonant imaging (MRI) which both showed two areas of vasogenic edema involving the subcortical white matter of left frontal and right posterior parasagittal regions, all autoimmune screens, infection workup from blood and CSF were negative, he underwent a brain biopsy that showed intense perivascular inflammation with neuronal loss and gliosis, findings are nonspecific and can be seen in a variety of condition. The patient's condition improved, and he was discharged without any complications. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14712334
Volume :
23
Issue :
1
Database :
Complementary Index
Journal :
BMC Infectious Diseases
Publication Type :
Academic Journal
Accession number :
174318892
Full Text :
https://doi.org/10.1186/s12879-023-08704-z