The Liaison between Metabolism and Oxidative Stress in Human Diseases.

This document discusses the relationship between metabolism and oxidative stress in human diseases. Mitochondria, which are responsible for ATP production, also produce reactive oxygen species (ROS) as a byproduct. Oxidative stress occurs when there is an imbalance between ROS production and antioxidant capacity, leading to cellular damage. The document explores the impact of mitochondrial dynamics, the interaction between mitochondria and the endoplasmic reticulum, and the role of oxidative stress in various diseases such as cancer, diabetes, cardiovascular disease, renal damage, neurodegenerative disorders, and ocular diseases. It also highlights the dual role of ROS in disease and the potential therapeutic strategies targeting metabolic pathways and phytochemicals. The document concludes by mentioning a special issue that focuses on these topics and lists the accepted papers for publication. [Extracted from the article]