Study Findings from Shenyang Pharmaceutical University Advance Knowledge in Pharmaceutics (Preparation of trans-Crocetin with High Solubility, Stability, and Oral Bioavailability by Incorporation into Three Types of Cyclodextrins).

A recent study conducted by researchers at Shenyang Pharmaceutical University in China has explored the potential use of inclusion complexes (ICs) of crocetin (CRT) with cyclodextrins (CDs) for oral administration. CRT is a compound found in saffron that has various pharmacological activities but is limited by its low stability and solubility. The researchers found that the ICs significantly improved the solubility, stability, and oral bioavailability of CRT, making it a promising option for applications in the food, healthcare, and pharmaceutical industries. The study provides valuable insights into the preparation and potential uses of CRT/CD ICs. [Extracted from the article]