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Increased Temporo-Spatial Dispersion of Repolarization During Double Premature Stimulation in the Intact Ventricle.

Authors :
Kobayashi, Yoshinori
Gotoh, Masamichi
Mandel, W. J.
Karagueuzian, Hrayr S.
Source :
Pacing & Clinical Electrophysiology; Nov1992, Vol. 15 Issue 11, p2194-2199, 6p
Publication Year :
1992

Abstract

The degree of temporo-spatial variation of repolarization during single (S<subscript>2</subscript>) and double (S<subscript>3</subscript>) premature stimulation was evaluated in five closed-chest anesthetized dogs. Monophasic action potentials (MAP) were simultaneously recorded with contact electrode and MAP duration (MAPD) restitution curves constructed from right ventricular (RVJ and left ventricular (LV) endocardial sites. At a given coupling interval, S<subscript>3</subscript> was associated with significantly greater dispersion of MAPD then S<subscript>2</subscript> (spatial dispersion, i.e., between RV and LV). Similarly, at a given diastolic interval, S<subscript>3</subscript> at RV and LV sites, was associated with significantly greater dispersion of MAPD then S<subscript>2</subscript> (temporal dispersion). It is concluded that S<subscript>3</subscript> is associated with greater temporo-spatial dispersion of repolarization then S<subscript>2</subscript>. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
01478389
Volume :
15
Issue :
11
Database :
Complementary Index
Journal :
Pacing & Clinical Electrophysiology
Publication Type :
Academic Journal
Accession number :
17452925
Full Text :
https://doi.org/10.1111/j.1540-8159.1992.tb03046.x