Findings in Leishmaniasis Reported from Mazandaran University of Medical Sciences (Developing Nanosize Carrier Systems for Amphotericin-b: a Review On the Biomedical Application of Nanoparticles for the Treatment of Leishmaniasis and Fungal...).

A recent study conducted by researchers at Mazandaran University of Medical Sciences in Sari, Iran, explores the development of nanosize carrier systems for Amphotericin-B (Am-B) in the treatment of Leishmaniasis and fungal infections. The researchers highlight the need for safe and effective drug delivery systems for Am-B due to issues such as organ cytotoxicity, low bioavailability, high costs, and technical problems associated with current formulations. They discuss the potential of nano-based technology and nanomaterials in designing novel drug delivery systems, including solid lipid nanostructured materials, liposomes, polymer and protein-based nanostructured materials, and more. These advancements in Am-B formulations show promise in the treatment of human systemic infections and are currently undergoing clinical tests. [Extracted from the article]