Studies from First Affiliated Hospital of Kunming Medical University Describe New Findings in Mesotheliomas (Mesothelin-targeted MRI for assessing migration, invasion, and prognosis in malignant pleural mesothelioma).

A recent study conducted at the First Affiliated Hospital of Kunming Medical University explored the role of mesothelin (MSLN) in the migration, invasion, and prognosis of malignant pleural mesothelioma (MPM). The researchers developed an MRI nanoprobe that targets MSLN to assess its status in vitro and in vivo. They found that MSLN expression was higher in the epithelial type of MPM and increased with tumor growth. The study concluded that this method could potentially aid in the early detection, histological subtype identification, and assessment of migration, invasion, and prognosis in MPM. [Extracted from the article]