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A meta‐analysis of topical Ketorolac's effect on surgical site wound healing post‐cataract surgery.

Authors :
You, Ran
Han, Yu
Source :
International Wound Journal; Jan2024, Vol. 21 Issue 1, p1-7, 7p
Publication Year :
2024

Abstract

This meta‐analysis evaluates the impact of topical ketorolac on surgical site wound healing and scar formation after cataract surgery. A thorough literature search, adhering to Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines, identified eight relevant studies from 2348 articles. The selected studies were analysed for wound healing efficacy, using the redness, edema, ecchymosis, discharge and approximation (REEDA) scale, and scar formation, assessed by the Manchester scar scale (MSS). Results indicated that ketorolac significantly improved wound healing, with lower REEDA scores 1 week post‐surgery (I2 = 97%; Random: standardised mean difference (SMD): −10.93, 95% CI: −13.85 to −8.00, p < 0.01), and reduced scar formation, evidenced by lower MSS scores 3 months post‐surgery (I2 = 74%; Random: SMD: −9.67, 95% CI: −11.03 to −8.30, p < 0.01). The findings suggest that topical ketorolac is beneficial in post‐cataract surgery care, enhancing wound healing and reducing scarring. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
17424801
Volume :
21
Issue :
1
Database :
Complementary Index
Journal :
International Wound Journal
Publication Type :
Academic Journal
Accession number :
175054792
Full Text :
https://doi.org/10.1111/iwj.14661