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A meta‐analysis of topical Ketorolac's effect on surgical site wound healing post‐cataract surgery.
- Source :
- International Wound Journal; Jan2024, Vol. 21 Issue 1, p1-7, 7p
- Publication Year :
- 2024
-
Abstract
- This meta‐analysis evaluates the impact of topical ketorolac on surgical site wound healing and scar formation after cataract surgery. A thorough literature search, adhering to Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines, identified eight relevant studies from 2348 articles. The selected studies were analysed for wound healing efficacy, using the redness, edema, ecchymosis, discharge and approximation (REEDA) scale, and scar formation, assessed by the Manchester scar scale (MSS). Results indicated that ketorolac significantly improved wound healing, with lower REEDA scores 1 week post‐surgery (I2 = 97%; Random: standardised mean difference (SMD): −10.93, 95% CI: −13.85 to −8.00, p < 0.01), and reduced scar formation, evidenced by lower MSS scores 3 months post‐surgery (I2 = 74%; Random: SMD: −9.67, 95% CI: −11.03 to −8.30, p < 0.01). The findings suggest that topical ketorolac is beneficial in post‐cataract surgery care, enhancing wound healing and reducing scarring. [ABSTRACT FROM AUTHOR]
- Subjects :
- WOUND healing
ONLINE information services
MEDICAL databases
META-analysis
CONFIDENCE intervals
SYSTEMATIC reviews
POSTOPERATIVE care
CATARACT surgery
TREATMENT effectiveness
SURGICAL site infections
QUALITY assurance
DESCRIPTIVE statistics
MEDLINE
ECCHYMOSIS
ODDS ratio
DATA analysis software
KETOROLAC
EDEMA
Subjects
Details
- Language :
- English
- ISSN :
- 17424801
- Volume :
- 21
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- International Wound Journal
- Publication Type :
- Academic Journal
- Accession number :
- 175054792
- Full Text :
- https://doi.org/10.1111/iwj.14661