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Risk Factors for Pediatric Invasive Group A Streptococcal Disease.
- Source :
- Emerging Infectious Diseases; Jul2005, Vol. 11 Issue 7, p1062-1066, 5p, 2 Charts
- Publication Year :
- 2005
-
Abstract
- Invasive group A Streptococcus (GAS) infections can be fatal and can occur in healthy children. A case-control study identified factors associated with pediatric disease. Case-patients were identified when Streptococcus pyogenes was isolated from a normally sterile site, and matched controls (≥2) were identified by using sequential-digit dialing. All participants were noninstitutionalized surveillance-area residents <18 years of age. Conditional regression identified factors associated with invasive disease: other children living in the home (odds ratio [OR] = 16.85, p = 0.0002) and new use of nonsteroidal anti-inflammatory drugs (OR - 10.64, p = 0.005) were associated with increased risk. More rooms in the home (OR = 0.67, p = 0.03) and household member(s) with runny nose (OR = 0.09, p = 0.002) were associated with decreased risk. Among children, household-level characteristics that influence exposure to GAS most affect development of invasive disease. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10806040
- Volume :
- 11
- Issue :
- 7
- Database :
- Complementary Index
- Journal :
- Emerging Infectious Diseases
- Publication Type :
- Academic Journal
- Accession number :
- 17521036
- Full Text :
- https://doi.org/10.3201/eid1107.040900