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Histone deacetylase 9 interacts with SiHAT3.1 and SiHDA19 to repress dehydration responses through H3K9 deacetylation in foxtail millet.
- Source :
- Journal of Experimental Botany; 2/2/2024, Vol. 75 Issue 3, p1098-1111, 14p
- Publication Year :
- 2024
-
Abstract
- Climate change inflicts several stresses on plants, of which dehydration stress severely affects growth and productivity. C<subscript>4</subscript> plants possess better adaptability to dehydration stress; however, the role of epigenetic modifications underlying this trait is unclear. In particular, the molecular links between histone modifiers and their regulation remain elusive. In this study, genome-wide H3K9 acetylation (H3K9ac) enrichment using ChIP-sequencing was performed in two foxtail millet cultivars with contrasting dehydration tolerances (IC403579, cv. IC4—tolerant, and IC480117, cv. IC41—sensitive). It revealed that a histone deacetylase, SiHDA9 , was significantly up-regulated in the sensitive cultivar. Further characterization indicated that SiHDA9 interacts with SiHAT3.1 and SiHDA19 to form a repressor complex. SiHDA9 might be recruited through the SiHAT3.1 recognition sequence onto the upstream of dehydration-responsive genes to decrease H3K9 acetylation levels. The silencing of SiHDA9 resulted in the up-regulation of crucial genes, namely, SiRAB18 , SiRAP2.4, SiP5CS2 , SiRD22 , SiPIP1;4 , and SiLHCB2.3 , which imparted dehydration tolerance in the sensitive cultivar (IC41). Overall, the study provides mechanistic insights into SiHDA9-mediated regulation of dehydration stress response in foxtail millet. [ABSTRACT FROM AUTHOR]
- Subjects :
- FOXTAIL millet
DEHYDRATION
DEACETYLATION
SIRTUINS
HISTONE acetylation
ACETYLATION
Subjects
Details
- Language :
- English
- ISSN :
- 00220957
- Volume :
- 75
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Journal of Experimental Botany
- Publication Type :
- Academic Journal
- Accession number :
- 175238884
- Full Text :
- https://doi.org/10.1093/jxb/erad425