Crooke Cell Adenoma Confers Poorer Endocrinologic Outcomes Compared with Corticotroph Adenoma: Results of a Multicenter, International Analysis.

This article, published in the Journal of Neurological Surgery, examines the outcomes of patients with Crooke cell adenomas (CCA) compared to those with corticotroph adenomas (sCTA), both of which are types of pituitary corticotroph adenomas found in patients with Cushing's disease. The study, which included 2,826 patients from 12 international centers, found that CCA patients had poorer endocrinologic outcomes compared to sCTA patients, despite having better local control rates and fewer residual tumors. The authors suggest that further research is needed to better understand CCA and develop more targeted treatment approaches. [Extracted from the article]