Patent Issued for Multifunctional protein molecules comprising decorin and use thereof (USPTO 11879009).

A patent has been issued for multifunctional protein molecules comprising decorin and their use. Angiogenesis, the formation of new blood vessels, is a crucial process in growth, wound healing, and cancer progression. Vascular endothelial growth factor (VEGF) is a protein that stimulates angiogenesis and is involved in various diseases. Checkpoint inhibitors are drugs that target proteins on cancer cells or T cells to enhance the immune system's ability to recognize and attack cancer cells. The patent describes multifunctional protein molecules that combine decorin with targeting polypeptides, such as antibodies, to inhibit VEGF or checkpoint proteins. These molecules have potential applications in inhibiting angiogenesis and treating cancer. [Extracted from the article]