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m6A 修饰调控酶及其结合蛋白在细胞自噬中 作用的研究进展.

Authors :
陈思琪
郭帅杰
周明学
Source :
Chinese Journal of Pathophysiology; Jan2024, Vol. 40 Issue 1, p157-163, 7p
Publication Year :
2024

Abstract

Autophagy is an important mechanism to maintain cellular function and metabolism, whereas abnormal autophagy can cause the advent and worsening of various diseases. N6-Methyladenosine( m6A) RNA methylation is a reversible RNA modification, which is regulated by m6A methyltransferase, m6A demethylase and m6A-binding protein. Studies have shown that autophagy-related genes promote or attenuate autophagy level dependent on the regulation of m6A, and then participate in the process of diseases. This paper reviews the progress of m6A modification regulatory enzymes and their binding proteins in regulating cell autophagy to provide reference for future researches. [ABSTRACT FROM AUTHOR]

Details

Language :
Chinese
ISSN :
10004718
Volume :
40
Issue :
1
Database :
Complementary Index
Journal :
Chinese Journal of Pathophysiology
Publication Type :
Academic Journal
Accession number :
175429353
Full Text :
https://doi.org/10.3969/j.issn.1000-4718.2024.00.002