Reports from Beijing Institute of Pharmacology and Toxicology Add New Study Findings to Research in Antigout Agents (Delivery Strategies for Colchicine as a Critical Dose Drug: Reducing Toxicity and Enhancing Efficacy).

A recent report from the Beijing Institute of Pharmacology and Toxicology discusses the delivery strategies for colchicine, a widely used natural drug for treating gout. The report highlights that while colchicine has potent anti-inflammatory effects, its clinical application is limited due to serious gastrointestinal adverse effects. The researchers explore different delivery strategies, including transdermal, injection, and oral routes, and emphasize the potential benefits of transdermal drug delivery in reducing toxicity and enhancing efficacy. The report also briefly discusses permeation-promoting technologies for transdermal drug delivery systems. This research provides scientific ideas and theoretical guidance for future studies on colchicine delivery strategies. [Extracted from the article]