New Breast Cancer Study Findings Have Been Reported by Investigators at Nanjing University [Dna Framework-controlled Poly(Mofs) As a Visual Platform for Diagnosis of Her2-positive Breast Cancer].

A recent study conducted at Nanjing University in China has reported new findings on the diagnosis of HER2-positive breast cancer. The study focuses on the controllable assembly of metal-organic frameworks (MOFs) using a DNA framework material. By regulating the number of phosphate groups that coordinate with catalytic Zr-MOFs, the researchers were able to create polymeric MOFs superstructures (Poly(MOFs)) with excellent catalytic activities and molecular recognition ability. The study also demonstrated the fabrication of a colorimetric biosensor for the quantification of HER2 protein, which showed promising results in distinguishing HER2-positive and triple-negative breast cancer patients. The research has been peer-reviewed and shows great potential for biomedical research and clinical applications. [Extracted from the article]