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Immunotherapeutic prospects and progress in bladder cancer.

Authors :
Liu, Junwei
Gao, Yue
Song, Chao
Liao, Wenbiao
Meng, Lingchao
Yang, Sixing
Xiong, Yunhe
Source :
Journal of Cellular & Molecular Medicine; Mar2024, Vol. 28 Issue 5, p1-7, 7p
Publication Year :
2024

Abstract

Bladder cancer is one of the most common malignant tumours of the urogenital system, with high morbidity and mortality. In most cases, surgery is considered the first choice of treatment, followed by adjuvant chemotherapy. However, the 5‐year recurrence rate is still as high as 65% in patients with non‐invasive or in situ tumours and up to 73% in patients with slightly more advanced disease at initial diagnosis. Various treatment methods for bladder cancer have been developed, and hundreds of new immunotherapies are being tested. To date, only a small percentage of people have had success with new treatments, though studies have suggested that the combination of immunotherapy with other therapies improves treatment efficiency and positive outcomes for individuals, with great hopes for the future. In this article, we summarize the origins, therapeutic mechanisms and current status of research on immunotherapeutic agents for bladder cancer. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
15821838
Volume :
28
Issue :
5
Database :
Complementary Index
Journal :
Journal of Cellular & Molecular Medicine
Publication Type :
Academic Journal
Accession number :
175750564
Full Text :
https://doi.org/10.1111/jcmm.18101