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Eu3+/Tb3+-modified Cd(II) coordination polymers for effective detection of uric acid and lung cancer biomarker N-acetylneuraminic acid.
- Source :
- Journal of Materials Chemistry C; 3/7/2024, Vol. 12 Issue 9, p3141-3153, 13p
- Publication Year :
- 2024
-
Abstract
- Nowadays, lung cancer is a severe health burden worldwide and the major challenge faced in this disease is that more than half of the patients are diagnosed in later stages. The measurement of N-acetylneuraminic acid (NANA) levels, an important biomarker, could serve as a useful indicator for the early diagnosis of this disease. In this work, 1D coordination polymer Cd-CP2 was obtained and explored as a luminescence probe for detecting the urinary biomarker uric acid (UA) via a quenching effect. The presence of free carboxylic groups in the coordination polymer leads to the formation of Eu<superscript>3+</superscript>/Tb<superscript>3+</superscript>-functionalized samples, named Eu<superscript>3+</superscript>@Cd-CP2 and Tb<superscript>3+</superscript>@Cd-CP2, via post-synthesis modification (PSM). Both of these samples were able to sense NANA via a ratiometric effect with the enhancement of ligand-centered peaks and quenching of rare earth peaks. The luminescence probe has several appealing merits, including a high selectivity, excellent sensitivity, low detection limit (0.89 μM for Eu<superscript>3+</superscript>@Cd-CP2 and 0.19 μM for Tb<superscript>3+</superscript>@Cd-CP2), and fast response time (less than 2 min). Furthermore, these fluorescent materials were explored as logic gates and test papers for potential application. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 20507526
- Volume :
- 12
- Issue :
- 9
- Database :
- Complementary Index
- Journal :
- Journal of Materials Chemistry C
- Publication Type :
- Academic Journal
- Accession number :
- 175769036
- Full Text :
- https://doi.org/10.1039/d3tc03775d