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Editorial: Synthetic peptide vaccine platforms targeting tumor-specific antigens: advances and challenges.

Authors :
Rubsamen, Reid M.
Sloan, Andrew E.
Source :
Frontiers in Pharmacology; 2024, p1-2, 2p
Publication Year :
2024

Abstract

This article is an editorial published in Frontiers in Pharmacology titled "Synthetic peptide vaccine platforms targeting tumor-specific antigens: advances and challenges." The authors discuss the discovery and therapeutic aspects of peptide vaccine platforms, specifically in relation to identifying potential antigen targets on tumors and strategies to enhance their immunogenicity. The article highlights advancements in computational techniques for identifying immunogenic peptide antigens, as well as the use of toll-like receptor agonists to improve the immunogenicity of vaccines. The authors emphasize the importance of confirming peptide binding characteristics through in-vivo or in-vitro determination. The article concludes by discussing the potential advantages of synthetic peptide vaccine platforms and the increasing tools available for designing peptide vaccines for oncology applications. [Extracted from the article]

Details

Language :
English
ISSN :
16639812
Database :
Complementary Index
Journal :
Frontiers in Pharmacology
Publication Type :
Academic Journal
Accession number :
175889001
Full Text :
https://doi.org/10.3389/fphar.2024.1363282