Myelodysplastic syndrome associated‐haemophagocytic lymphohistiocytosis: A retrospective study of 15 cases in a single centre.

This article presents a retrospective study on myelodysplastic syndrome-associated haemophagocytic lymphohistiocytosis (MDS-HLH), a rare condition characterized by blood disorders and immune system abnormalities. The study found that MDS-HLH is underexplored in previous literature and provided insights into its clinical characteristics and treatment outcomes. Patients in the study exhibited bone marrow dysplasia and karyotypic abnormalities, and the timing of HLH onset correlated with the risk of MDS. Treatment should prioritize controlling HLH, although the prognosis for MDS-HLH remains poor. The study was conducted ethically and the raw data will be available for non-commercial use. [Extracted from the article]