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A comparative study of the benefits of monotherapy rosiglitazone versus rosiglitazone with insulin in streptozotocin-induced diabetes in rats.

Authors :
Prabhu, Ramesh
Shankarappa, Deepak
Senthil G.
Kumar P., Venkata Naveen
Kumar, Jai
Source :
National Journal of Physiology, Pharmacy & Pharmacology; 2024, Vol. 14 Issue 3, p450-454, 5p
Publication Year :
2024

Abstract

This article presents a comparative study on the benefits of different treatments for rats with streptozotocin-induced diabetes. The study found that a combination therapy of insulin, rosiglitazone, and gemfibrozil was more effective in controlling blood sugar and lipid levels compared to individual treatments. The combination therapy also had a positive effect on lipid levels, reducing cholesterol and triglycerides while increasing HDL. The study suggests that this combination therapy may help prevent cardiovascular events associated with diabetes. [Extracted from the article]

Details

Language :
English
ISSN :
23204672
Volume :
14
Issue :
3
Database :
Complementary Index
Journal :
National Journal of Physiology, Pharmacy & Pharmacology
Publication Type :
Academic Journal
Accession number :
176017535
Full Text :
https://doi.org/10.5455/njppp.2023.13.03114202309082023