Findings in Biosensors Reported from College of Biomedical Engineering (Aptamer-based Biosensors for Point-of-care Testing).

A recent study from the College of Biomedical Engineering in Wuhan, China, explores the use of aptamer-based biosensors for point-of-care testing (POCT). POCT is a diagnostic technology that allows for rapid and cost-effective analysis, enabling patients to obtain clinically relevant results through self-testing. The study highlights the importance of aptamers, which are molecular probes capable of recognizing multiple targets, in biomedical sensors for molecular recognition. The researchers discuss various strategies to improve the selection efficiency and affinity of aptamers, as well as signal amplification techniques using nucleic acids, self-assembly, and enzyme-based reactions. They also explore the use of nanomaterials and the development of electrochemical and optical sensors for POCT. The study concludes that aptamer-based POCT sensors have an advantage in detecting small molecules and multi-channel detection. [Extracted from the article]