Development of Gamma-Delta T-Cell Therapies: Activation and expansion are essential for success in both autologous and allogeneic therapies.

The article focuses on the development of gamma-delta T-cell therapies for cancer treatment, highlighting their unique mechanisms and potential advantages over traditional Alfa-Beta T-cell therapies. Topics discussed include the recognition pattern of gamma-delta T cells, their role in immune responses against pathogens and tumors, and strategies for enhancing their killing capability through genetic engineering and combination therapies.