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Development and characterization of 40 InDel markers from the major histocompatibility complex genes of largemouth bass (Micropterus salmoides)

Authors :
Zhang, Meng
Wang, Zerui
Cui, Jiao
Ma, Xiao
Qiao, Zhigang
Kong, Xianghui
Xu, Ruwei
Li, Shengjie
Du, Jinxing
Zhao, Chunlong
Source :
Molecular Biology Reports; 2024, Vol. 51 Issue 1, p1-8, 8p
Publication Year :
2024

Abstract

Background: The genetic improvement in growth and food habit domestication of largemouth bass (Micropterus salmoides) have made breakthroughs in past decades, while the relevant work on disease resistance were rarely carried out. Major histocompatibility complex (MHC) genes, which are well known as their numbers and high polymorphisms, have been used as candidate genes to mine disease-resistant-related molecular markers in many species. Methods and results: In present study, we developed and characterized 40 polymorphic and biallelic InDel markers from the major histocompatibility complex genes of largemouth bass. The minor allele frequency, observed heterozygosity, expected heterozygosity and polymorphic information content of these markers ranged from 0.0556 to 0.5000, 0.1111 to 0.6389, 0.1064 to 0.5070, and 0.0994 to 0.3750, respectively. Three loci deviated significantly from Hardy-Weinberg equilibrium, while linkage disequilibrium existed at none of these loci. Conclusion: These InDel markers might provide references for the further correlation analysis and molecular assisted selection of disease resistance in largemouth bass. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
03014851
Volume :
51
Issue :
1
Database :
Complementary Index
Journal :
Molecular Biology Reports
Publication Type :
Academic Journal
Accession number :
176380856
Full Text :
https://doi.org/10.1007/s11033-024-09429-1