New Limb-Girdle Muscular Dystrophies Study Results Reported from Qazvin University of Medical Sciences (Clinical and Genetic Characteristics of Limb-girdle Muscular Dystrophy In Iranian Patients).

A recent study conducted at Qazvin University of Medical Sciences in Iran focused on limb-girdle muscular dystrophy (LGMD), a muscle disease characterized by weakness in the shoulder and pelvic girdle. The study aimed to determine the genetic diversity and frequency of different forms of LGMD in Iranian children. The researchers analyzed data from 41 patients and found that alpha and beta sarcoglycanopathy were the most prevalent phenotypes. The severity of clinical involvement was found to be predicted by SGCB gene mutation and sarcoglycan expression. This research provides valuable insights into the clinical and genetic characteristics of LGMD in Iranian patients. [Extracted from the article]