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Application of chimeric antigens to paper-based diagnostics for detection of West Nile virus infections of Crocodylus porosus: a novel animal test case.
- Source :
- Zika & Mosquito Week; 4/12/2024, p222-222, 1p
- Publication Year :
- 2024
-
Abstract
- A preprint abstract from biorxiv.org discusses the development of a novel diagnostic test for West Nile virus (WNV) infections in crocodiles. The researchers created a lateral flow assay (LFA) using chimeric viral antigens derived from the Binjari virus (BinJV) and modified to display the outer proteins of WNV. The LFA demonstrated 100% sensitivity and specificity in detecting WNV seroconversion in crocodiles, with results obtained in less than 15 minutes. The researchers suggest that this method could be adapted for detecting vector-borne virus infections in humans and other animals. However, it is important to note that this preprint has not yet undergone peer review. [Extracted from the article]
Details
- Language :
- English
- Database :
- Complementary Index
- Journal :
- Zika & Mosquito Week
- Publication Type :
- Periodical
- Accession number :
- 176441918