Investigators from University of Edinburgh Have Reported New Data on Arthrodesis (Transfemoral Amputation Versus Knee Arthrodesis for Failed Total Knee Replacement: a Systematic Review of Outcomes).

A systematic review conducted by investigators from the University of Edinburgh compared the outcomes of transfemoral amputation (TFA) and knee arthrodesis (KA) as salvage options for failed total knee replacement (TKR). The review included 44 papers with a total of 470 TFA patients and 1034 KA patients. The findings indicated that KA patients were more likely to achieve independent bipedal ambulation compared to TFA patients. However, both treatment cohorts had relatively common occurrences of subsequent infection and revision surgery. The study highlights the need for randomized controlled trials comparing TFA and KA. [Extracted from the article]