Editorial: Advances of novel approaches to enhance therapeutic efficacy and safety in human solid cold tumor.

This article explores the potential of immunotherapy in treating cancer, specifically focusing on "cold tumors" that are resistant to traditional treatments. Immunotherapy offers high specificity and minimal side effects by stimulating the body's immune response against tumors. The article discusses innovative approaches to enhance the effectiveness and safety of immunotherapy, such as discovering new biomarkers, reshaping the tumor microenvironment, and exploring combination therapies. It also highlights emerging therapies like DNA/RNA vaccines. However, there are still challenges in translating these strategies into clinical practice, emphasizing the need for further research and the discovery of new targets to advance tumor immunotherapy. [Extracted from the article]