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Functional roles of circular RNAs in lung injury.

Authors :
Fei-Fei Gao
Dian-Qing Chen
Yue-Tong Jiang
Cui-Fei Han
Bi-Yun Lin
Zhan Yang
Juan-Hua Quan
Ying-Huan Xiong
Xin-Tian Chen
Source :
Frontiers in Pharmacology; 2024, p1-11, 11p
Publication Year :
2024

Abstract

Lung injury leads to respiratory dysfunction, low quality of life, and even lifethreatening conditions. Circular RNAs (circRNAs) are endogenous RNAs produced by selective RNA splicing. Studies have reported their involvement in the progression of lung injury. Understanding the roles of circRNAs in lung injury may aid in elucidating the underlying mechanisms and provide new therapeutic targets. Thus, in this review, we aimed to summarize and discuss the characteristics and biological functions of circRNAs, and their roles in lung injury from existing research, to provide a theoretical basis for the use of circRNAs as a diagnostic and therapeutic target for lung injury. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
16639812
Database :
Complementary Index
Journal :
Frontiers in Pharmacology
Publication Type :
Academic Journal
Accession number :
176641245
Full Text :
https://doi.org/10.3389/fphar.2024.1354806