Titelbild: Modular Weaving DNAzyme in Skeleton of DNA Nanocages for Photoactivatable Catalytic Activity Regulation (Angew. Chem. 18/2024).

The article titled "Modular Weaving DNAzyme in Skeleton of DNA Nanocages for Photoactivatable Catalytic Activity Regulation" discusses the achievement of spatiotemporal control of catalytic DNAzyme activity. The researchers, Lele Li, Mengyuan Li, and others, have successfully woven activatable DNAzyme into the skeleton of tetrahedral DNA nanocages. This technique allows for efficient intracellular delivery with improved biostability and enables light-triggered on-demand liberation of DNAzyme, providing conditional control of catalytic gene regulation function. In another study, researchers synthesized silole and disila-cyclooctene derivatives through reactions between silicon atoms and dibrominated molecules, which have potential applications in surface chemistry. [Extracted from the article]